ALPROLIX^®: the first EHL FIX
WITH >10 years OF REAL-WORLD EXPERIENCE^1–3

TROUGH LEVEL MAY NOT PREDICT EFFICACY
ALPROLIX was the only EHL FIX with zero bleeds in patients¹⁰

A survey of centres treating patients with EHL FIXs (N=67) across the US and Canada showed:¹⁰

Performance of EHL FIXs varied in clinical practice¹⁰

Proportion of patients with spontaneous or poorly controlled bleeding¹⁰

Survey suggests that despite achieving plasma troughs >10%, patients may have
differential responses to EHL FIX, noted in the rFIX-FP and rFIX-GP cohorts¹⁰

EHL, extended half-life; FIX, factor IX; rFIX-FP, recombinant factor IX albumin fusion protein; rFIX-GP, recombinant glycopegylated factor IX.

Investigating the use and performance of EHL and SHL FIX in clinical practice¹⁰

EHL, extended half-life; FIX, factor IX; SHL, standard half-life.

No safety data were collected.